Spironolactone is used to treat high blood pressure and heart failure. Follow all directions on your prescription label and read all medication guides or instruction sheets. You should use spironolactone with caution if you have kidney problems, high levels of potassium in your blood, Addison's disease, if you are unable to urinate, or if you are also taking eplerenone. 1-3.3 … Store at room temperature away from heat, light, and moisture. Brand Name: Aldactone, CaroSpir. Diagnostic dose: It may not be safe to breastfeed while using spironolactone. Your doctor should decide whether you take spironolactone if you are pregnant. Spironolactone is a medicine used to treat people with various conditions, including high blood pressure, low potassium levels, heart failure, edema, liver disease, … During spironolactone therapy, mean blood pressure … Usual Adult Dose for Congestive Heart Failure: Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL. Uses: Applies to the following strengths: 25 mg; 100 mg; 50 mg; 25 mg/5 mL. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. High blood pressure is found among people who take Spironolactone, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. Comments: The median dose of spironolactone was 25 mg (interquartile range: 25 to 50 mg) at both the start and end of the observation period. Your reactions could be impaired. Pediatric: Among therapeutic options recommended by the National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and … You may need to stop for a short time. Using spironolactone with other drugs that make you dizzy can worsen this effect. Spironolactone tablets are usually administered in conjunction with other heart failure therapies. Drug class: aldosterone receptor antagonists. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. From the limited available evidence, spironolactone appears to lower blood pressure compared to placebo to a similar degree in patients with primary (essential) hypertension when doses of 100-500 mg/day … In patients with severe heart failure (New York Heart Association [NYHA] class III to IV), discontinue or interrupt treatment for serum potassium greater than 5 mEq/L or for serum creatinine greater than 4 mg/dL. once or twice a day. Your doctor may have you take this as one single dose … Spironolactone has an average rating of 5.4 out of 10 from a total of 33 ratings for the treatment of High Blood Pressure. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. You can also take … Spironolactone is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood). They reduce the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure. Other drugs may interact with spironolactone, including prescription and over-the-counter medicines, vitamins, and herbal products. Copyright 1996-2021 Cerner Multum, Inc. -Short-term preoperative treatment of patients with primary hyperaldosteronism. The right dosage of spironolactone depends on the severity of acne. Generic Name: spironolactone (spir ON oh LAK tone) Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL The phase IV clinical study is created by eHealthMe based on reports of 78,343 people who have side effects when taking Spironolactone … To determine the clinical effect of spironolactone on blood pressure, patients were followed for several weeks. In patients with severe heart failure, monitor potassium and creatinine one week after initiation or a dose increase, monthly for the first 3 months, then quarterly for a year, and then every 6 months. In case you do not clear in a month, the dosage can range up to 200mg/day … Uses: When eplerenone is used, it should be prescribed at approximately double the effective dose of spironolactone and used twice daily when used in doses higher than 50 mg daily. As a result, spironolactone helps treat high blood pressure brought on by hyperaldosteronism. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. -Short test: 400 mg orally per day for 4 days What is the strength of CaroSpir (spironolactone) oral suspension? The dose is usually 100 to 400 milligrams (mg) per day to prepare for surgery. Last updated on April 14, 2020. Off-label, spironolactone … Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Take spironolactone exactly as prescribed by your doctor. -A second diuretic that acts more proximally at the renal tubule may be added if adequate diuresis has not been achieved after 5 days. “I was prescribed Spironolactone 25 mg, to take with my Hydrochlorothiazide (HCTZ 25 mg), for high blood pressure and low potassium levels. -Patients tolerant of initial dose: May increase to 50 mg orally once a day as clinically indicated Subsequently, the dose may be adjusted according to patient response. Consult WARNINGS section for additional precautions. Medically reviewed by Drugs.com. Do not use potassium supplements or salt substitutes, unless your doctor has told you to. Drug class: aldosterone receptor antagonists. Spironolactone is a potassium-sparing diuretic FDA-approved to treat a variety of conditions, including edema, heart failure, high blood pressure and an over abundance of the hormone aldosterone. Contraindicated in patients with anuria, acute renal insufficiency, or significant impairment of renal excretory function. Aldactone (spironolactone) is a diuretic (water pill) used to treat a number of different problems including primary aldosteronism (an imbalance in hormones that causes high blood pressure), heart failure, high blood pressure… Duration of therapy: Treatment should be continued for at least 2 weeks to achieve a maximum response. It’s given as a single dose … Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. You may report side effects to FDA at 1-800-FDA-1088. Having congestive heart failure, cirrhosis, or uncontrolled high blood pressure during pregnancy may lead to medical problems in the mother or the baby. amlodipine, lisinopril, metoprolol, losartan, furosemide, hydrochlorothiazide, carvedilol, spironolactone, Lasix, potassium chloride. You may take spironolactone with or without food, but take it the same way each time. USES: Spironolactone is used to treat high blood pressure.Lowering high blood pressure … This product is available in the following dosage … Get emergency medical help if you have signs of an allergic reaction to spironolactone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Talk to … -TUMORIGENICITY: This drug has been shown to be a tumorigen in chronic toxicity studies of rats. High blood pressure often has no symptoms. Tell your … Aldactone (spironolactone) is a medication that's used to treat many different disorders, from high blood pressure to fluid retention. Dosage for high blood pressure (hypertension) Adult dosage (ages 18–64 years) The typical starting dosage is 25–100 mg taken by mouth each day. -For the long test, correction of hypokalemia and hypertension provides presumptive evidence of primary hyperaldosteronism. Tell any doctor who treats you that you are using spironolactone. Usual Adult Dose for Edema 25 to 200 mg orally per day in single or divided doses Duration of therapy: When given as the sole diuretic, continue the initial dose for at least … Uses: Call your doctor for medical advice about side effects. Just after I took Spironolactone with my HCTZ … This medicine is available only with your doctor's prescription. 25 to 200 mg orally per day in single or divided doses, Initial dose: 50 to 100 mg orally per day in single or divided doses. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use spironolactone only for the indication prescribed. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Medically reviewed by Sanjai Sinha, MD. It is also prescribed in the treatment of congestive heart failure, cirrhosis … Anyhow, doctors usually recommend either 50mg/day or 100mg/day i.e. -Patients intolerant of initial dose: May decrease to 25 mg orally every other day If you need surgery, tell your surgeon you currently use this medicine. Select one or more newsletters to continue. Tell your doctor about all your other medicines, especially: heart or blood pressure medicine (especially another diuretic); NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. Tumors in animals but it is not known whether this could occur in people hypokalemia and hypertension provides evidence! 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